Duromine 15 mg drug is designed to treat obesity. Dosage of Duromine for weight reduction can be different because of the personal characteristics of each patient.

The doctor takes into account a variety of details before determining the correct dose of the medication to treat obesity. Here the following aspects can be distinguished:

  • sex;
  • age;
  • body weight;
  • incidence rate.

A packaging of Duromine 15 mg contains 30 capsules. Duromine 15 mg capsules are made of gelatin in gray-green color with the indicated dosage. Each capsule contains a complex of ion-exchange resin, which releases the active ingredient Phentermine.

Phentermine (phenyl tertiary butylamine) is a sympathomimetic amine, similar to amphetamine in its chemical characteristics. Influencing on the hypothalamus, Phentermine suppresses appetite.

The active ingredient Phentermine has a strong effect on the dopaminergic and noradrenergic nervous systems.

Duromine 15 mg drug may also have peripheral effects associated with lipid metabolism. Heart rate may increase.

Duromine 15 mg contains a complex of ion-exchange resin and active ingredient Phentermine. The ion exchange resin is insoluble.

The pharmacological effect of Duromine 15 mg drug for weight loss does not appear until the moment of reaction with cations:

  • sodium
  • hydrogen;
  • potassium, etc.

The release rate of the active ingredient Phentermine depends on the cations concentration. Phentermine is rapidly absorbed from the gastrointestinal tract. Approximately 70-80% of this drug for treating obesity is excreted unchanged in the urine. The rest of the active ingredient is metabolized by the liver.

The half-life of Phentermine is approximately 25 hours. As studies show, acidification of urine can reduce the half-life up to 7-8 hours.

Side effects of Duromine 15 mg anti-obesity drug may include dry mouth, vomiting, mood swings, and heart palpitations.

Other side effects of Duromine 15 mg may also occur. Inform the attending physician or pharmacist about any changes of your state of health.

Since anti-obesity drug Duromine 15 mg can be addictive, tell your doctor about any changes in the medication intake.