Metermine is used for treatment of overweight or various classes of obesity. Antihypertensive drugs are the best treatment method for patients with hypertension and prevention of complications associated with this disease, such as myocardial infarction or stroke.

Weight problems are often accompanied with high blood pressure.

These diseases often need to be treated simultaneously. Therefore, many people are interested in information about Metermine interaction with antihypertensive drugs.

Metermine with antihypertensive agents can be taken in two situations:

  • If you overweight or obesity are accompanied with hypertension.
  • If intake of Metermine capsules causes increase of blood pressure.

It should be noted that Metermine should not be taken by patients with severe hypertension or pulmonary arterial hypertension. Before to start taking Metermine, these diseases should be treated.

If hypertension is mild or moderate, use of antihypertensive drugs is not a contraindication to Metermine use.

The list of drugs contraindicated during Metermine-therapy includes:

  • Other centrally acting anorectic agents.
  • Recent or concurrent use of MAOI.

Metermine sometimes interacts with antihypertensive, psychotropic and sympathomimetic agents. Therefore, they should be taken with caution. It is necessary to assess benefit-risk balance before to start combined use.

The decision to use Metermine with any other drugs should be taken by an experienced specialist in obesity treatment. Constant monitoring of the heart function and cardiovascular system is required.

Use of a sphygmomanometer is the easiest way to control blood pressure. Sphygmomanometer can be used at home and special skills are not required for this.

Metermine interaction with any other drugs may cause side effects. Choice one of the types of antihypertensive drugs will reduce risk of side effects.

Today, the following drugs are used to control or treat high blood pressure:

  • Vasodilators
  • ACE inhibitors
  • Renin inhibitors
  • Diuretics
  • Benzodiazepines
  • Aldosterone receptor antagonists
  • Calcium channel blockers
  • Alpha-2 adrenergic receptor agonists
  • Angiotensin II receptor antagonists
  • Adrenergic receptor antagonists

Many factors, such as mechanism of drug action, the patient’s age, mental illnesses, diabetes, chronic diseases of internal organs or kidney stones affect choice of one of antihypertensive agents. Therefore, a medical practitioner with experience in treatment of obesity and cardiovascular diseases must do this choice.

It is possible that the daily dose of Metermine and / or antihypertensive agent will need to be reduced at the beginning of treatment. Gradual increase in the daily dose will minimize risks of Metermine interaction with antihypertensive drugs.

If lists of side effects of Metermine and antihypertensive agents have the same items, the risk of their occurrence increases. For example, common side effects of Metermine and ACE inhibitors are headache, fatigue or dizziness.

Benzodiazepines may play a certain role in lowering blood pressure, but hypertension is not the main indication for prescribing this class of drugs.

  • Benzodiazepines and Metermine may interact.

They affect the central nervous system and therefore, they should not be used together, unless the doctor has instructed otherwise.

Diuretics have been used for a long time and they are some of the cheapest antihypertensive agents.

If there are no contraindications, the doctor may prescribe Metermine in combination with diuretics.
Decrease in blood pressure is not the mechanism of action of Metermine.

The drug should be taken in conjunction with changes in lifestyle that have a beneficial effect on the heart function and cardiovascular system. In addition, the drug reduces body weight and this greatly reduces the risk of hypertension.